Endocrine Abstracts

Background: Non-alcoholic fatty liver disease (NAFLD), encompasses hepatic steatosis alone (NAFL), steatohepatitis (NASH), NAFL/NASH with fibrosis and cirrhosis. Severe fibrosis and cirrhosis are associated with increased risk of morbidity and mortality (due to cardiovascular events, end-stage liver failure and cancer). Postmenopausal women are a high-risk group of patients that have worse outcomes, but the specific factors that place them at higher risk are incompletely under...

Background: Non-alcoholic liver disease (NAFLD) affects up to 30% of adults worldwide. With the prevalence of NAFLD increasing after menopause, women aged >55 years are more likely to progress to advanced fibrosis than men. Moreover, liver decompensation secondary to NAFLD is more frequent in women compared to men. However, the causes of these differential outcomes are not fully understood.Methodology: We performed a retrospective cohort study utilis...

Introduction: The relationship between non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes is well-established. However, the precise impact of glucose control on the severity and progression of NAFLD remains largely unexplored. Currently, none of the non-invasive scoring systems used to assess NAFLD severity incorporate glucose control markers, such as glycated hemoglobin (HbA1c).Methods: Data were collected fr...